Powdered extract of Protium heptaphyllum with high triterpene content.
KEY ACTIONS
RAW MATERIAL
CHARACTERISTIC MOLECULES
ACTION
Bioactive molecules contained in Protium resin have attracted increasing interest over the years; several studies have shown interesting hepatoprotective, antinociceptiveand anti-inflammatory properties.
In particular, thepentacyclic and tetracyclic triterpenes that characterise this extract are able to modulate the release of endogenous cholesterol in hepatocytes through a mechanism that acts by regulating the gene expression of key enzymes involved in cholesterolandfatty acid metabolism.
RAW MATERIAL
Protium
Protium heptaphyllum (Aubl.) Marchand is an evergreen tree belonging to the Burseraceae family, widespread in the Amazon Forest. Gummi-resin obtained as exudate of the trunk has been used since ancient times by local populations for its pain relieving and anti-inflammatory properties.
In particular, thepentacyclic and tetracyclic triterpenes that characterise this extract are able to modulate the release of endogenous cholesterol in hepatocytes through a mechanism that acts by regulating the gene expression of key enzymes involved in cholesterolandfatty acid metabolism.
The consumption of Protium resin can bring several benefits to the body, promoting better digestive function, better liver function and promoting the body’s natural defenses.
Protium
Protium heptaphyllum (Aubl.) Marchand is an evergreen tree belonging to the Burseraceae family, widespread in the Amazon Forest. Gummi-resin obtained as exudate of the trunk has been used since ancient times by local populations for its pain relieving and anti-inflammatory properties.
In particular, thepentacyclic and tetracyclic triterpenes that characterise this extract are able to modulate the release of endogenous cholesterol in hepatocytes through a mechanism that acts by regulating the gene expression of key enzymes involved in cholesterolandfatty acid metabolism.
The consumption of Protium resin can bring several benefits to the body, promoting better digestive function, better liver function and promoting the body’s natural defenses.
FORMULATIONS
Hepamyr® is available in:
- POWDER FORMULATION
The chemical characterisation uses a validated method based on gas chromatography coupled to mass spectrometry (GC-MS) and flame ionisation detector (GC-FID) and on high performance liquid chromatography coupled to mass spectrometry (HPLC-MS/MS).
Hepamyr® is standardised and titrated at 20% w/w penta- and tetra-cyclic triterpenes (sum of acid and neutral fraction); this allows accurate dosing in various galenic and nutraceutical forms.
INSIGHTS
