Fluid and powder extracts of Boswellia sacra and Boswellia serrata gummi-resin with a high content of AKBA, boswellic acids and cembrenes
KEY ACTIONS
RAW MATERIALS
CHARACTERISTIC MOLECULES
ACTION
Boswellic acids are known to have healing properties; acting as inhibitors of importantinflammatory markers such as NF-kB, 5-lipoxygenase and 2-cyclooxygenase, they counteract the production of pro-inflammatory cytokines and leukotrienes for broad-spectrum benefit.
Recent studies have shown that the serratol (or cembrenol) present in B. serrata is a potent transient receptor potential vanilloid 3 (TRPV3) agonist, a heat-sensitive ion channel expressed in keratinocytes and the central nervous system.
The TRPV3 receptor has considerable physiological implications, such as inflammatory processes, body weight management, depressive symptoms and brain function
Incensol acetate, typical of B. sacra, is a selective TRPV3 agonist capable of stimulating channel-mediated calcium influx; in addition, incensol is a potent inhibitor of IL-6-induced STAT3 and a potentinhibitor of NF-kB.
RAW MATERIALS
Boswellia
Boswellia genus plants belong to the Burseraceae family and are famous to produce incense(olibanum), a gummi-resin obtained by drying the exudate from the trunk of these trees in the sun.
The use of olibanum dates to ancient times: local people have always used it for its aromatic and healing properties, mainly in cosmetics, religious rituals, cultural ceremonies and natural medicine.
There are several species, but the most renowned for incense production are Boswellia sacraFlueck. (syn.B. carteri Birdw), typical of the Horn of Africa, and Boswellia serrataRoxb from India.
Boswellia
Boswellia genus plants belong to the Burseraceae family and are famous to produce incense(olibanum), a gummi-resin obtained by drying the exudate from the trunk of these trees in the sun.
The use of olibanum dates to ancient times: local people have always used it for its aromatic and healing properties, mainly in cosmetics, religious rituals, cultural ceremonies and natural medicine.
There are several species, but the most renowned for incense production are Boswellia sacraFlueck. (syn.B. carteri Birdw), typical of the Horn of Africa, and Boswellia serrataRoxb from India.
FORMULATIONS
BosLiq® is available in:
- BosLiq AKBA (fluid and powder), made from Boswellia sacra gummi-resin
- BosLiq BA (powder), made from Boswellia serrata gummi-resin
Chemical characterisation is based on high-performance liquid chromatography coupled with mass spectrometry for the identification and authentication of boswellic acids and on gas chromatography coupled with mass spectrometry (GC-MS) and flame ionisation detector (GC-FID) for the characterisation of total diterpenes.
BosLiq®-AKBA is standardised and titrated in boswellic acids and AKBA; this allows accurate dosing in various galenic and nutraceutical forms as it is available in both fluid (25% w/w, of which AKBA 4% w/w) and powder form (25% w/w, of which AKBA 5% w/w).
BosLiq®-BA is standardised and titrated in total boswellic acids and allows accurate dosing in various galenic and nutraceutical forms as it is available in 10% w/w powder form.
INSIGHTS
INSIGHTS ABOUT BosLiq®
